Norbash A M, Pelc N J, Shimakawa A, Enzmann D R
Department of Radiology, Stanford University School of Medicine, CA 94305-5105.
Radiology. 1994 Feb;190(2):560-4. doi: 10.1148/radiology.190.2.8284416.
To present a spin-echo phase-contrast (SEPC) magnetic resonance pulse sequence designed to measure the very slow flow in ventricular shunt tubing.
A flow phantom constructed of shunt tubing and incorporating no valve or a high-, medium-, or low-pressure valve was connected to a flow pump. Flow rates were 0.05-1.00 mL/min (72-1,440 mL/d). Flow measurement was performed with the thin-section SEPC sequence.
The flow rates measured with SEPC imaging correlated closely with the pump flow rate for the entire physiologic spectrum of shunt flow rates. This was true for all valves, resulting in overall R2s of .974 at 4 cm/sec and .980 at 2 cm/sec. Shunt flow was pulsatile with valves in place. There was a linear relationship between flow rate and the frequency of valve opening and closing.
The SEPC technique is an accurate and noninvasive method of measuring shunt flow.
介绍一种自旋回波相位对比(SEPC)磁共振脉冲序列,用于测量脑室分流管中非常缓慢的血流。
将由分流管构成且包含无瓣膜或高、中、低压瓣膜的流动模型连接到流量泵。流速为0.05 - 1.00毫升/分钟(72 - 1440毫升/天)。使用薄层SEPC序列进行流量测量。
对于分流流速的整个生理范围,SEPC成像测量的流速与泵流速密切相关。所有瓣膜的情况均如此,在4厘米/秒时总体R2值为0.974,在2厘米/秒时为0.980。有瓣膜时分流血流呈搏动性。流速与瓣膜开闭频率之间存在线性关系。
SEPC技术是一种准确且无创的测量分流血流的方法。