[成年大鼠血浆和肝脏中胆固醇水平的调节]

[Regulation of cholesterol levels in plasma and liver of adult rats].

作者信息

Chevallier F, Mathé D, Lutton C

出版信息

C R Acad Hebd Seances Acad Sci D. 1976 Dec 20;283(16):1759-62.

Abstract

The dynamics of cholesterol-system in the plasma is characterized by a parameter which is a linear function of the internal secretion of cholesterol. So, the level of plasma cholesterol from synthesis is a low as its flow is high. Moreover, the level of plasma cholesterol from diet is simultaneously proportional to the flow of cholesterol intestinal absorption and dependent on the dynamics controlled by the internal secretion. The laws of the cholesterolemia cumulate these partial laws. Similar relations concern the esterified cholesterol in the liver.

摘要

血浆中胆固醇系统的动态变化由一个参数表征，该参数是胆固醇内分泌的线性函数。因此，合成产生的血浆胆固醇水平较低，因为其流动速度较高。此外，饮食来源的血浆胆固醇水平与胆固醇肠道吸收的流速同时成正比，并取决于内分泌控制的动态变化。胆固醇血症的规律累积了这些部分规律。类似的关系也适用于肝脏中的酯化胆固醇。