Kershisnik M, Callender D L, Batsakis J G
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Ann Otol Rhinol Laryngol. 1993 Dec;102(12):967-70. doi: 10.1177/000348949310201211.
The head and neck is the most frequent location for extraneuraxial meningiomas, be they wholly extracranial or extraspinal or extensions of central nervous system meningiomas. Regardless of anatomic site of origin, nearly all meningiomas arise from meningocytes of arachnoid granulations. Ectopic arachnoid cell clusters have a predilection for areas of dural penetration of cranial nerves, and it is in these areas that most extracranial meningiomas are found. Surgical excision is the mainstay of treatment and must be planned by radiologic studies to determine the extent of the tumor and the presence or absence of a companion central nervous system meningioma. The often locally invasive and aggressive behavior of the meningiomas belies their benign histologic appearance.
头颈部是轴外脑膜瘤最常见的部位，无论是完全位于颅外或脊柱外，还是中枢神经系统脑膜瘤的延伸。无论起源的解剖部位如何，几乎所有脑膜瘤都起源于蛛网膜颗粒的脑膜细胞。异位蛛网膜细胞团倾向于位于脑神经硬膜穿透区域，而大多数颅外脑膜瘤正是在这些区域被发现。手术切除是主要的治疗方法，必须通过影像学检查来规划，以确定肿瘤的范围以及是否存在伴发的中枢神经系统脑膜瘤。脑膜瘤通常具有局部侵袭性和侵袭性行为，这与其良性的组织学表现不符。
