Frantz R, Xakellis G C, Arteaga M
Decubitus. 1993 Nov;6(6):16-20.
Although the physiological effects of pressure on tissue have been demonstrated in the animal model, little is known about its effect in ill, elderly patients who are at risk for pressure ulcers. This study describes the pattern of dermal blood flow during a period of constant, low-level, compressive pressure in this population of patients. Dermal blood flow was measured over the trochanter of 16 elderly (> 60 years) subjects who were defined as at risk for pressure ulcer development by the Braden Scale for Predicting Pressure Ulcer Risk. Using a laser-Doppler velocitometer, blood flow at baseline and during 60 minutes of left-side lying on an air mattress were measured. Mean blood flow at baseline was 0.79 (SD 0.43). Following 60 minutes of compressive pressure, mean blood flow was 0.65 (SD 0.87). Blood flow tracings during the 60-minute period of continuous, compressive pressure revealed an inconsistent pattern of response; the flow increased, decreased, or showed no change. This distribution of responses suggests that significantly more variability in blood flow response exist in at-risk individuals than was previously believed.
尽管压力对组织的生理影响已在动物模型中得到证实，但对于其在有发生压疮风险的患病老年患者中的作用却知之甚少。本研究描述了该患者群体在持续低水平压迫期间的皮肤血流模式。对16名年龄大于60岁的老年受试者的转子部位进行皮肤血流测量，这些受试者根据预测压疮风险的Braden量表被定义为有发生压疮的风险。使用激光多普勒血流仪，测量基线时以及在气垫床上左侧卧位60分钟期间的血流。基线时的平均血流为0.79（标准差0.43）。在60分钟的压迫压力后，平均血流为0.65（标准差0.87）。在持续60分钟的压迫压力期间的血流描记显示出不一致的反应模式；血流增加、减少或无变化。这种反应分布表明，有风险个体的血流反应变异性比之前认为的要大得多。
