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疱疹样皮炎与确诊的乳糜泻。

Dermatitis herpetiformis and established coeliac disease.

作者信息

Gawkrodger D J, Vestey J P, O'Mahony S, Marks J M

机构信息

University Department of Medicine, Royal Hallamshire Hospital, Sheffield, U.K.

出版信息

Br J Dermatol. 1993 Dec;129(6):694-5. doi: 10.1111/j.1365-2133.1993.tb03333.x.

DOI:10.1111/j.1365-2133.1993.tb03333.x
PMID:8286252
Abstract

Fifteen (5.3%) of 282 patients with dermatitis herpetiformis (DH) were diagnosed as suffering from coeliac disease before the onset of their DH. This group showed a female preponderance, and a later than usual onset of DH. The mean age at which DH developed was 40.0 years, and there was a mean interval of 13.2 years between the two diagnoses. Seven patients had stopped their gluten-free diet, and a further four were poor compliers. Persistent gluten ingestion in coeliacs with a specific genetic predisposition may result in the development of DH.

摘要

282例疱疹样皮炎(DH)患者中有15例(5.3%)在DH发病前被诊断为患有乳糜泻。该组女性居多,且DH发病年龄较晚。DH发病的平均年龄为40.0岁,两次诊断之间的平均间隔为13.2年。7例患者已停止无麸质饮食,另有4例依从性差。具有特定遗传易感性的乳糜泻患者持续摄入麸质可能导致DH的发生。

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