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Investigations of oligodeoxyinosine for triple helix formation.

作者信息

Hogeland J S, Weller D D

机构信息

Department of Chemistry, Oregon State University, Corvallis 97331.

出版信息

Antisense Res Dev. 1993 Fall;3(3):285-90. doi: 10.1089/ard.1993.3.285.

DOI:10.1089/ard.1993.3.285
PMID:8286929
Abstract

The ability of a 17-mer of deoxyinosine to form a triple helix with a (dT)17(dA)17 segment of a 29-mer Watson-Crick duplex was investigated. Under conditions amenable to triple helix formation, (dT)17 showed evidence of complex formation as evidenced by UV melting curves and gel mobility shift assays whereas (dI)17 did not.

摘要

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