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神经生理学技术在潜水相关疾病研究中的贡献。

The contribution of neurophysiologic techniques to the investigation of diving-related illness.

作者信息

Murrison A W

机构信息

Undersea Medicine Division, Institute of Naval Medicine, Alverstoke, Gosport, Hants, UK.

出版信息

Undersea Hyperb Med. 1993 Dec;20(4):347-73.

PMID:8286989
Abstract

This review considers the important role of experimental and clinical neurophysiologic techniques in the investigation of diving-related illness. The invasive monitoring of neural function using evoked potentials has been central to the creation of animal models of neurologic decompression illness (DCI). Such models have produced important insights into the nature of DCI and have reduced the empiricism of treatment protocols. However, caution is required in the application of neurophysiologic data from animal models of the disease to human DCI. Conflicting evidence exists for the usefulness of electroencephalographic and evoked potential studies in the investigation of acute neurologic DCI in man. Some neurophysiologic evidence has been produced to support the contention that diving may cause subclinical injury to the central nervous system.

摘要

本综述探讨了实验性和临床神经生理学技术在潜水相关疾病研究中的重要作用。利用诱发电位对神经功能进行侵入性监测一直是创建神经减压病(DCI)动物模型的核心。此类模型为深入了解DCI的本质提供了重要见解,并减少了治疗方案的经验性。然而,将该疾病动物模型的神经生理学数据应用于人类DCI时需谨慎。关于脑电图和诱发电位研究在人类急性神经型DCI调查中的有用性,存在相互矛盾的证据。已产生一些神经生理学证据来支持潜水可能导致中枢神经系统亚临床损伤这一论点。

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