Dawson D A, Archer L D
Division of Biometry and Epidemiology, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD 20857.
Addiction. 1993 Nov;88(11):1509-18. doi: 10.1111/j.1360-0443.1993.tb03136.x.
Data from a national representative sample of US adults were analyzed to determine the association between the relative frequency of heavy drinking (the proportion of drinking occasions on which 5+ drinks were consumed) and past-year alcohol dependence, adjusting for the influences of average ethanol intake and sociodemographic factors. Fifty-seven percent of current drinkers reported never drinking 5+ drinks, and 21% drank 5+ drinks at least once but on less than 10% of all drinking occasions. Nine percent reported drinking 5+ drinks on at least half of all drinking occasions. Average daily intake was positively correlated with the relative frequency of heavy drinking, and both consumption measures were positively associated with the risk of alcohol dependence. Increases in either relative frequency of heavy drinking or average ethanol intake reduced, but did not eliminate, the effect of the other on the risk of dependence. The excess risk of dependence associated with frequent heavy drinking varied among population subgroups and was increased by age, education, and female gender.
对来自美国成年人全国代表性样本的数据进行了分析，以确定重度饮酒的相对频率（饮用5杯及以上酒水的饮酒场合所占比例）与过去一年酒精依赖之间的关联，并对平均乙醇摄入量和社会人口学因素的影响进行了校正。57%的当前饮酒者表示从未饮用过5杯及以上酒水，21%的人至少有一次饮用过5杯及以上酒水，但在所有饮酒场合中所占比例不到10%。9%的人报告称在至少一半的饮酒场合中饮用过5杯及以上酒水。平均每日摄入量与重度饮酒的相对频率呈正相关，且这两种饮酒量指标均与酒精依赖风险呈正相关。重度饮酒相对频率或平均乙醇摄入量的增加会降低但不会消除另一个因素对依赖风险的影响。与频繁重度饮酒相关的额外依赖风险在不同人群亚组中有所不同，且随着年龄、教育程度和女性性别而增加。
