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柯萨奇B病毒性心肌炎与扩张型心肌病的免疫状态及病理学

Immunological status and pathology of coxsackie B viral myocarditis and dilated cardiomyopathy.

作者信息

Chen S X, Mei S W, Bao S H, Zheng X J, Chang P L, Yao J S, Yao S, Zhang D Q

机构信息

Cardiological Department of Renji Hospital, Shanghai Second Medical University.

出版信息

Chin Med J (Engl). 1993 Sep;106(9):659-64.

PMID:8287699
Abstract

The changes in 15 cases of viral myocarditis and 28 cases of dilated cardiomyopathy were reported and compared, which were the pathological changes of endomyocardial biopsy; NK cells activity; % of peripheral T lymphocytes and its subsets determined by using OKT3,4,8 (OKT3-peripheral total lymphocytes; OKT4-helper cells; OKT8-suppressive cells) monoclonal antibody; values of immunoglobulin IgG, IgA, IgM; titer of coxsackie B antibody neutralization test. And a discussion on their relationship was included.

摘要

报告并比较了15例病毒性心肌炎和28例扩张型心肌病的变化,这些变化包括心内膜活检的病理变化、NK细胞活性、使用OKT3、4、8(OKT3-外周血总淋巴细胞;OKT4-辅助细胞;OKT8-抑制细胞)单克隆抗体测定的外周血T淋巴细胞及其亚群百分比、免疫球蛋白IgG、IgA、IgM值、柯萨奇B抗体中和试验滴度。并对它们之间的关系进行了讨论。

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