Iida M, Kobayashi H, Matsumoto T, Okada M, Fuchigami T, Yao T, Fujishima M
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Dis Colon Rectum. 1994 Jan;37(1):16-21. doi: 10.1007/BF02047208.
The postoperative course of intestinal Behçet's disease was studied in nine patients who had undergone a total of 15 operations due to intestinal ulcers.
These patients were followed up for an average of 6.0 years (range, 1 year, 3 months to 13 years, 10 months) after each operation and they were repeatedly examined by double-contrast radiography and/or colonofiberscopy.
Recurrence of intestinal ulcers was observed in 12 (80 percent) of the 15 surgical cases. The incidence (50 percent) of postoperative recurrence in six cases in which intraoperative endoscopy revealed no abnormality in the retained intestine was lower than that (100 percent) in nine cases without this examination. Recurrent intestinal lesions in most cases were demonstrated as multiple aphthoid ulcers in the ileum near the ileocolectomy, or as one or two deep ulcers at the ileocolectomy site. The recurrent ulcers were successfully treated by various medical therapies, but the effectiveness of these therapies was only temporary.
In the case of this disease, intraoperative endoscopy may be useful for preventing postoperative recurrence and periodic follow-up examination with radiography and endoscopy should be performed, even after surgery.
对9例因肠道溃疡共接受15次手术的肠道白塞病患者的术后病程进行研究。
这些患者在每次手术后平均随访6.0年（范围为1年3个月至13年10个月），并通过双重对比造影和/或结肠镜检查反复进行检查。
15例手术病例中有12例（80%）出现肠道溃疡复发。术中内镜检查显示保留肠段无异常的6例患者术后复发率（50%）低于未进行此项检查的9例患者（100%）。大多数复发性肠道病变表现为回盲部切除术附近回肠的多发性口疮样溃疡，或回盲部切除部位的一两个深部溃疡。复发性溃疡通过各种药物治疗成功治愈，但这些治疗的效果只是暂时的。
对于这种疾病，术中内镜检查可能有助于预防术后复发，即使在手术后也应定期进行影像学和内镜随访检查。
