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用无水乙醇进行内镜治疗肠道白塞病术后复发性溃疡及单纯性溃疡。

Endoscopic therapy with absolute ethanol for postoperative recurrent ulcers in intestinal Behçet's disease, and simple ulcers.

作者信息

Matsukawa M, Yamasaki T, Kouda T, Kurihara M

机构信息

Department of Gastroenterology, Toyosu Hospital, Showa University, Tokyo, Japan.

出版信息

J Gastroenterol. 2001 Apr;36(4):255-8. doi: 10.1007/s005350170112.

Abstract

BACKGROUND

When examined macroscopically and histologically, there are no differences between "simple" intestinal ulcers and intestinal ulcers of Behçet's disease. The postoperative recurrence of intestinal Behçet's disease and simple ulcers was frequently. Medical treatment for postoperative recurrent ulcers is palliative, and the patient often requires surgery. We studied about an effect of absolute ethanol spraying via endoscopy for the ulcers.

METHOD

The postoperative rate of recurrence was 56% (9/16). Commonly the ulcer recurred around the anastomotic region. We performed spraying for recurrent ulcers with absolute ethanol via endoscope in four patients.

RESULTS

This therapy was effective for the recurrent ulcer in the 4 patients. In this study, the patients who were monitored and treated by the spraying of ethanol did not require further surgery.

CONCLUSIONS

This therapy should performed for recurrent ulceration in cases of simple ulcer and intestinal Behçet's disease.

摘要

背景

在宏观和组织学检查中,“单纯性”肠道溃疡与白塞病肠道溃疡之间并无差异。肠道白塞病和单纯性溃疡术后复发频繁。术后复发性溃疡的药物治疗只是姑息性的,患者常需手术治疗。我们研究了内镜下喷洒无水乙醇对溃疡的疗效。

方法

术后复发率为56%(9/16)。溃疡通常在吻合口区复发。我们对4例复发性溃疡患者通过内镜用无水乙醇进行喷洒。

结果

该疗法对4例复发性溃疡有效。在本研究中,接受乙醇喷洒监测和治疗的患者无需进一步手术。

结论

对于单纯性溃疡和肠道白塞病的复发性溃疡应采用该疗法。

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