Halouzka R, Nevole M
Vet Med (Praha). 1976 Sep;21(9):565-72.
Histologically were investigated 37 cases of neoplastic growths and 2 cases of hyperplasia in canine sebaceous glands. From this number 24 tumours of circumanal glands (20 adenomas and 4 carcinomas) and 13 tumours of sebaceous glands in extraanal localization were found. The average age of affected dogs was 9 years. In the neoplastic tissue of circumanal adenomas three differentiation degrees of sebaceous cells were identified. Biological behaviour is favourable, tumours destructured the tissue only topically. Malignant neoplasias consisted of tumorously proliferated, lowly differentiated sebaceous cells. Tumours observed in the ear and external ear canal are histologically similar to human cutaneous sebaceous gland adenomas and therefore from the viewpoint of comparative oncology they are important. In therapy, surgical extirpation is applied with possible estrogen combination.
对犬皮脂腺的37例肿瘤性生长和2例增生进行了组织学研究。其中发现24例肛周腺肿瘤（20例腺瘤和4例癌）以及13例肛门外皮脂腺肿瘤。患病犬的平均年龄为9岁。在肛周腺瘤的肿瘤组织中，鉴定出皮脂腺细胞的三个分化程度。生物学行为良好，肿瘤仅局部破坏组织。恶性肿瘤由肿瘤性增殖的低分化皮脂腺细胞组成。在耳朵和外耳道观察到的肿瘤在组织学上与人类皮肤皮脂腺腺瘤相似，因此从比较肿瘤学的角度来看它们很重要。在治疗中，采用手术切除并可能联合雌激素。
