Ning T, Bronzino J D
Department of Engineering and Computer Science, Trinity College, Hartford, CT 06106.
IEEE Trans Biomed Eng. 1993 Sep;40(9):870-6. doi: 10.1109/10.245607.
The paper discusses the use of nonlinear bispectral analysis in examining the hippocampal EEG collected at subfields of CA1 and the dentate gyrus during the vigilance state of REM sleep. The cross-bispectrum and its unique capabilities of detecting and quantifying quadratic nonlinear interactions occurring between these two hippocampal subfields are explained and demonstrated with simulation examples and EEG data. It was found in this study that quadratic nonlinear interactions exist between CA1 and the dentate gyrus in the 6-8 frequency band which dominates the theta (theta) rhythm observed in the hippocampal EEG during REM sleep. As a result, energy components around the frequency band of the second-order harmonics of theta rhythm are not totally spontaneous, but generated largely due to quadratic nonlinear interactions.
本文讨论了非线性双谱分析在检查快速眼动睡眠警觉状态下CA1亚区和齿状回海马脑电信号中的应用。通过仿真示例和脑电数据解释并展示了交叉双谱及其检测和量化这两个海马亚区之间二次非线性相互作用的独特能力。本研究发现，在6-8频段内，CA1和齿状回之间存在二次非线性相互作用，该频段主导了快速眼动睡眠期间海马脑电中观察到的θ节律。因此，θ节律二次谐波频段周围的能量成分并非完全自发产生，而是主要由二次非线性相互作用产生。
