Finkelstein S M, Lindgren B, Prasad B, Snyder M, Edin C, Wielinski C, Hertz M
Dept. of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis 55455.
Heart Lung. 1993 Nov-Dec;22(6):523-33.
To demonstrate that home spirometry measurements are reliable and valid and can be used as part of a home measurement monitoring system by lung transplant recipients.
Longitudinal, observational.
University medical center.
Eighteen patients who have undergone lung transplantation; age range was 24 to 63 years (mean of 49.5 years).
Reliability and validity of forced expiratory volume at 1 second (FEV1) and forced vital capacity (FVC).
Recording of spirometry, vital signs, and symptom measures at home each day by use of a paperless electronic diary/spirometer instrument.
Day-to-day variability as measured by the standard deviation ranged from 0.013 L to 0.202 L for FVC and 0.015 L to 0.117 L for FEV1. The correlation between the two best forced expiratory maneuvers on any given day was 0.98 for both FVC and FEV1, with percent differences between the measurements of 2% for FVC and 3% for FEV1. The correlation between measurements performed in the pulmonary function laboratory and measurements done by the patient at home on the same day was 0.94 for FVC and 0.99 for FEV1.
This evaluation demonstrated that home measurements are both reliable (i.e., repeatable) and valid when compared with the "gold standard" of the pulmonary function laboratory. The home monitoring program has been well accepted by patients, is easy to use, and provides data comparable to that collected during clinic visits.
证明家庭肺量计测量是可靠且有效的，并且可以被肺移植受者用作家庭测量监测系统的一部分。
纵向观察性研究。
大学医学中心。
18例接受肺移植的患者；年龄范围为24至63岁（平均49.5岁）。
1秒用力呼气容积（FEV1）和用力肺活量（FVC）的可靠性和有效性。
使用无纸电子日记/肺量计仪器，让患者每天在家记录肺量计测量结果、生命体征和症状指标。
FVC的标准差测量的每日变异性范围为0.013L至0.202L，FEV1为0.015L至0.117L。在任何给定日期，两次最佳用力呼气动作之间的FVC和FEV1相关性均为0.98，测量值之间的百分比差异FVC为2%，FEV1为3%。肺功能实验室测量结果与患者同日在家测量结果之间的相关性，FVC为0.94，FEV1为0.99。
该评估表明，与肺功能实验室的“金标准”相比，家庭测量既可靠（即可重复）又有效。家庭监测计划已被患者广泛接受，使用方便，并提供与门诊就诊时收集的数据相当的数据。
