McQueen D, McKillop J H, Gray H W, Callaghan M, Monaghan C, Bessent R G
Department of Gynaecology, Western Infirmary of Glasgow, UK.
Hum Reprod. 1993 Nov;8(11):1910-4. doi: 10.1093/oxfordjournals.humrep.a137959.
The migration of radionuclide through the genital tract was observed, comparing 20 patients with endometriosis and infertility with a control group of 23 infertile patients who had a normal pelvis. All patients had patent tubes at laparoscopy and chromopertubation, performed in both groups for the investigation of infertility and to diagnose the presence and extent of endometriosis. A radionuclide tubal test, using human albumin microspheres labelled with 99m-technetium (99mTc) was subsequently undertaken to observe the extent of genital tract migration of radionuclide to uterus, Fallopian tube and peritoneal cavity. The results show that radionuclide migration to the peritoneal cavity was impaired in patients with endometriosis, compared with the control group (30 versus 83%, respectively; P < 0.001). There was no relationship between migration and the severity of endometriosis. We conclude that impaired tubal function may be a cause of infertility in some patients with endometriosis.
观察了放射性核素在生殖道中的迁移情况，将20例患有子宫内膜异位症和不孕症的患者与23例骨盆正常的不孕对照患者进行了比较。两组患者均在腹腔镜检查和输卵管通液术时输卵管通畅，进行这些检查是为了调查不孕情况以及诊断子宫内膜异位症的存在和程度。随后进行了一项放射性核素输卵管检查，使用标记有99m-锝（99mTc）的人白蛋白微球来观察放射性核素在生殖道向子宫、输卵管和腹腔迁移的程度。结果显示，与对照组相比，子宫内膜异位症患者放射性核素向腹腔的迁移受到损害（分别为30%和83%；P<0.001）。迁移与子宫内膜异位症的严重程度之间没有关系。我们得出结论，输卵管功能受损可能是一些子宫内膜异位症患者不孕的原因。
