Iturralde M, Venter P F
Semin Nucl Med. 1981 Oct;11(4):301-14. doi: 10.1016/s0001-2998(81)80027-x.
A radionuclide procedure, hysterosalpingo-radionuclide scintigraphy (HERS), was designed to evaluate the migration of a particulate radioactive tracer from the vagina to the peritoneal cavity and ovaries as well as to image and functionally outline the patency of the pathways between these two extremes of the female reproductive system. Technetium-99m human albumin microspheres (99mTc-HAM) were deposited in the posterior fornices of patients who were divided into two specific groups. Group I consisted of patients who were to undergo different elective gynecologic operations, in which besides obtaining sequential images, radioactivity levels were measured in the removed organs and tissues. Group II consisted of patients referred by the Infertility Clinic for evaluation of their reproductive system pathways patency. In this latter group, HERS was compared with contrast hysterosalpingography (HSG) and peritoneoscopy (PCP). The results obtained from measurements of radioactivity levels on the removed surgical specimens and comparison with other conventional gynecologic diagnostic procedures provide accurate evidence of the migration of 99mTc-HAM from the vagina, through the uterus and tubes, to the peritoneal cavity and ovaries, and show that HERS is a simple noninvasive method for functionally imaging and assessing the patency of the female reproductive system pathways.
一种放射性核素检查方法，即子宫输卵管放射性核素闪烁造影术（HERS），旨在评估颗粒状放射性示踪剂从阴道向腹腔和卵巢的迁移情况，以及对女性生殖系统这两个极端部位之间通道的通畅性进行成像和功能勾勒。将锝-99m人白蛋白微球（99mTc-HAM）注入患者阴道后穹窿，患者被分为两个特定组。第一组由即将接受不同择期妇科手术的患者组成，除了获取连续图像外，还对切除的器官和组织进行放射性水平测量。第二组由不孕不育门诊转诊来评估其生殖系统通道通畅性的患者组成。在这后一组中，将HERS与子宫输卵管造影（HSG）和腹腔镜检查（PCP）进行了比较。从切除的手术标本上测量放射性水平并与其他传统妇科诊断程序进行比较所获得的结果，为99mTc-HAM从阴道经子宫和输卵管迁移至腹腔和卵巢提供了准确证据，并表明HERS是一种用于对女性生殖系统通道进行功能成像和评估通畅性的简单无创方法。
