艾滋病病毒HIV-1的起源。
The origin of HIV-1, the AIDS virus.
作者信息
Siefkes D
出版信息
Med Hypotheses. 1993 Oct;41(4):289-99. doi: 10.1016/0306-9877(93)90069-3.
Abstract
This article proposes a series of experiments to determine if cows and sheep could be used as animal models for HIV-1, the AIDS virus. To justify this effort, a substantial case is presented that HIV-1 is a natural recombinant of Bovine Leukemia Virus (BLV) and Visna Virus. This natural recombinant may have been inadvertently transferred to humans through the Intensified Smallpox Eradication Program conducted in sub-Saharan Africa in the late 1960s and most of the 1970s.
摘要
本文提出了一系列实验，以确定牛和羊是否可作为艾滋病病毒HIV-1的动物模型。为了证明这一研究的合理性，文中提出了一个重要观点，即HIV-1是牛白血病病毒（BLV）和维斯纳病毒的天然重组体。这种天然重组体可能是在20世纪60年代末和70年代大部分时间于撒哈拉以南非洲开展的强化天花根除计划期间无意间传播给人类的。
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