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[呋喃唑酮或卡巴多司在早期断奶仔猪起始料中的作用]

[The effect of furazolidone or carbadox in the starter mixture for early-weaned piglets].

作者信息

Dvorák M, Herzig I

出版信息

Vet Med (Praha). 1976 Oct;21(10):597-607.

PMID:828986
Abstract

For a period of 14 days, piglets from six litters, weaned between the 25th and 28th day of age, were fed the COS 2 starter containing either a premix with furazolidone or carboadox of Czechoslovak origin. Bentonite hydrosilicate was used as a carrier in both cases. Furazolidone administered in the dose of 200 mg per 1 kg of feed prevented diarrhoea, insignificantly increased body weight gain, and decreased the consumption of feed per 1 kg of gain from 5.6 kg in the control to 4.0 kg in the test animals. Carbadox administered in the dose of 50 mg per 1 kg of feed suppressed the signs of enteritis in comparison with the control piglets, significantly increased body weight gains, and reduced feed consumption to 1.9 kg per 1 kg of gain. No differences were recorded in the concentration of blood glucose, total protein, and total cholesterol in plasma. The control piglets showed increased parameters of the adrenocortical function. The proportion (percentage) of haemolytic E. coli in rectum was affected neither by carbadox nor by furazolidone; furazolidone suppressed the occurrence of lactoso-negative strains. An insignificant drop of the number of haemolytic E. coki in the duodenum and jejunum of the furazolidone-and carbadox-treated piglets was observed after 14 days. With their clinical effects, the two substances tested manifest themselves as suitable for the reduction of losses in weaned piglets.

摘要

在14天的时间里,对6窝在25至28日龄断奶的仔猪饲喂含有捷克斯洛伐克产的含呋喃唑酮或卡巴氧预混料的COS 2仔猪开食料。两种情况下均使用水合硅酸膨润土作为载体。每1千克饲料中添加200毫克呋喃唑酮可预防腹泻,使体重增加不明显,并使每增加1千克体重的饲料消耗量从对照组的5.6千克降至试验动物的4.0千克。每1千克饲料中添加50毫克卡巴氧与对照仔猪相比,抑制了肠炎症状,显著增加了体重增加,并使每增加1千克体重的饲料消耗量降至1.9千克。血浆中血糖、总蛋白和总胆固醇的浓度未记录到差异。对照仔猪肾上腺皮质功能参数升高。直肠中溶血性大肠杆菌的比例(百分比)既不受卡巴氧也不受呋喃唑酮的影响;呋喃唑酮抑制了乳糖阴性菌株的出现。14天后,观察到呋喃唑酮和卡巴氧处理的仔猪十二指肠和空肠中溶血性大肠杆菌数量有不明显下降。从临床效果来看,所测试的这两种物质显示出适合减少断奶仔猪的损失。

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