Lim P S, Lin J L, Hu S A, Huang C C
Department of Internal Medicine, Kuang Tien General Hospital, Taichung, Taiwan, Republic of China.
Ren Fail. 1993;15(5):639-44. doi: 10.3109/08860229309069416.
Gallbladder toxin of the grass carp (Ctenopharyngodon idella) is a less well-known cause of acute renal failure. Three cases are reported and the diagnosis is primarily clinical. All our patients presented initially with gastrointestinal upset including nausea, vomiting, diarrhea, and abdominal fullness. These symptoms usually occurred with 10 min to 18 h after the ingestion the raw gallbladder of the grass carp. All our cases developed acute renal failure and in two of them toxic hepatitises were noted. An acute tubular necrosis was demonstrated on renal biopsy in one of our patients. The treatment is mainly supportive and two of them received hemodialysis. All three cases recovered, with normal renal and liver functions 2-4 weeks after the incident. A review of the cases previously reported in the English literature is presented.
草鱼（Ctenopharyngodon idella）胆囊毒素是急性肾衰竭鲜为人知的病因。本文报告3例，诊断主要基于临床症状。我们所有患者最初均出现胃肠道不适，包括恶心、呕吐、腹泻和腹胀。这些症状通常在摄入生草鱼胆囊后10分钟至18小时出现。我们所有病例均发展为急性肾衰竭，其中2例出现中毒性肝炎。1例患者肾活检显示急性肾小管坏死。治疗主要是支持性治疗，其中2例接受了血液透析。所有3例均康复，事件发生后2至4周肾功能和肝功能恢复正常。本文还对英文文献中先前报道的病例进行了综述。
