Nyska A, Harmelin A, Sandbank J, Scolnik M, Waner T
Kimron Veterinary Institute, Department of Pathology, Beit Dagan, Israel.
Toxicol Pathol. 1993;21(4):397-401. doi: 10.1177/019262339302100408.
A case of a spontaneous intratubular spermatic seminoma is described in a 98-wk-old Fischer-344 (F-344) rat. The differential diagnosis of spermatic seminoma from the other morphological forms of the tumor was based on the recognition of 3 cell types. The tumor cells were positive for S-100 antigen and cytokeratin. To the best of our knowledge, this is the second case of a seminoma reported in an F-344 rat and the first dealing with electron microscopic and immunohistochemical features of this tumor.
本文描述了一例98周龄的Fischer-344（F-344）大鼠发生的自发性精索精原细胞瘤。精原细胞瘤与其他形态学类型肿瘤的鉴别诊断基于对三种细胞类型的识别。肿瘤细胞S-100抗原和细胞角蛋白呈阳性。据我们所知，这是F-344大鼠中报道的第二例精原细胞瘤病例，也是首例涉及该肿瘤电子显微镜和免疫组织化学特征的病例。
