Vallat A V, Cariou G, Arborio M, Lesourd A, Cochand-Priollet B
Services Centraux d'Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, Paris.
Arch Anat Cytol Pathol. 1996;44(2-3):109-12.
In this case report concerning a testicular tumor, the difficulty of discriminating between embryonic carcinoma with granulomatous reaction and anaplastic seminoma is described. According to the literature and the findings of the present case, the value of immunohistochemical investigations is emphasized, especially the use of anti cytokeratin antibody in the diagnosis of embryonic carcinoma. Therapeutic issues stress the importance of such a diagnosis. Furthermore the immunohistochemical identification of embryonic carcinoma in every case should lead to a new classification of the so-called anaplastic seminoma's entity.
在这份关于睾丸肿瘤的病例报告中,描述了鉴别伴有肉芽肿反应的胚胎癌和间变性精原细胞瘤的困难。根据文献和本病例的发现,强调了免疫组化检查的价值,尤其是抗细胞角蛋白抗体在胚胎癌诊断中的应用。治疗问题凸显了这种诊断的重要性。此外,在每一病例中通过免疫组化鉴定胚胎癌应会导致对所谓间变性精原细胞瘤实体的重新分类。