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[食管癌围手术期多模式治疗策略]

[Perioperative multi-modality treatment strategies in esophageal cancer].

作者信息

Porschen R

机构信息

Abteilung für Gastroenterologie der Medizinischen Klinik und Poliklinik, Heinrich-Heine-Universität Düsseldorf.

出版信息

Z Gastroenterol. 1993 Nov;31(11):680-5.

PMID:8291282
Abstract

In order to improve the prognosis of patients with cancer of the esophagus, perioperative combined treatment modalities have been designed. The positive effect of an additional preoperative chemotherapy and of a pre- or postoperative radiotherapy has not been proven consistently until now. Neoadjuvant radiochemotherapy induces a pathohistologic complete remission in one quarter of the patients. The results of radiochemotherapy without operation in esophageal carcinomas look promising. However, their exact value has still to be investigated in randomized studies.

摘要

为改善食管癌患者的预后,已设计了围手术期联合治疗模式。迄今为止,术前额外化疗以及术前或术后放疗的积极效果尚未得到一致证实。新辅助放化疗可使四分之一的患者实现病理组织学完全缓解。食管癌单纯放化疗的结果看起来很有前景。然而,其确切价值仍有待在随机研究中进行探究。

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