Cook S D, Troiano R, Bansil S, Dowling P C
Neurology Service, VA Medical Center, East Orange, NJ.
Adv Neurol. 1994;64:83-95.
Gestation is a period of decreased risk for a relapse of MS, whereas the 3 months postpartum is a period of high risk. Taken together, the pregnancy year may also be a period of higher risk for relapse than non-pregnancy periods. However, the lifetime risk rate does not appear to change because of pregnancy, and on the basis of current retrospective studies, long-term disability is not higher in pregnant women or even women experiencing relapses during the pregnancy year. MS has little or no effect on the course of pregnancy or delivery, although patients with severe MS may have difficulty fully caring for their newborns. The decision to become pregnant should be made by the patient and her husband after they are appropriately informed about the risks involved.
妊娠期间是多发性硬化症（MS）复发风险降低的时期，而产后3个月是高风险期。综合来看，妊娠年的复发风险可能也高于非妊娠时期。然而，终生风险率似乎不会因妊娠而改变，根据目前的回顾性研究，孕妇甚至在妊娠年复发的女性，其长期残疾情况并不更严重。MS对妊娠或分娩过程几乎没有影响，不过重度MS患者可能在充分照顾新生儿方面存在困难。是否怀孕的决定应由患者及其丈夫在充分了解相关风险后做出。
