Nesterova V I, Chebotareva M A
Vopr Med Khim. 1976 Nov-Dec;22(6):732-5.
Content of thiamine and activities of two enzymes were studied in blood cells of patients with various types of leukosis. In patients with acute leukemia content of thiamin was decreased in leucocytes and blood plasma. Content of vitamin B1 was increased in erythroid cells of peripheric blood in erythroleukosis. Administration of thiamin into some patients caused a distinct increase in its content in blood cells. The guanosine phosphorylase activity was higher in blood cells in leukosis as compared with control. The transketolase activity was not distinctly altered.
研究了各类白血病患者血细胞中硫胺素的含量及两种酶的活性。急性白血病患者的白细胞和血浆中硫胺素含量降低。红白血病患者外周血红细胞中的维生素B1含量增加。给部分患者补充硫胺素后,其血细胞中的硫胺素含量显著增加。与对照组相比,白血病患者血细胞中的鸟苷磷酸化酶活性更高。转酮醇酶活性无明显变化。