Iñigo Riesgo C A, Solórzano Martín C J, Delgado Caro G, Valdivia Cárdenas S O, Gómez Partida G
Hospital Gineco, Centro Médico Nacional de Occidente (CMNO) del Instituto Mexicano del Seguro Social (IMSS) en Guadalajara Jalisco, México.
Ginecol Obstet Mex. 1998 Nov;66:435-9.
Percutaneous mitral valvuloplasty with Inoue balloon was performed in seven pregnant women with severe mitral stenosis in NYHA state III or IV that were unresponsive to conventional management Usual technique was performed with echocardiographic score of 8 or less except one and average gestational age of 28.5 +/- 6.4 weeks. The mean mitral gradient was 19.8 +/- 6.4 mmHg, and decreased to 3.6 +/- 2.9 mmHg (P < 0.01) and valvular area increased from 0.84 +/- 0.01 to 2.2 +/- 0.05 (P < 0.01) in 5 from 7 (P < 0.05) there was minimal mitral incompetence, there were no cases of atrial septal defect. Two patients had moderate to severe pulmonary hypertension which decreased immediately after treatment. All patients showed an improvement (P < 0.001) in the clinical state. Mean fetal exposure to radiation was seven minutes and the patients had two transesophageal echocardiography done during the procedure. One patient had to be taken to open commissurotomy due to perforation of the aorta which caused minimal hematoma. In two patients transient fetal bradycardias were noted during the hypotensive episodes caused by balloon inflation with no serious fetal distress. All but one pregnancies got to term; four patients delivered vaginally and three underwent cesarean section due to obstetric indication. Neonatal weight and Apgar score were satisfactory. We consider that the significative benefits of the procedure, together with zero maternal and fetal mortality make this technique an acceptable one for this pathology.
对7例纽约心脏协会(NYHA)心功能Ⅲ级或Ⅳ级的重度二尖瓣狭窄孕妇进行了经皮Inoue球囊二尖瓣成形术,这些孕妇对传统治疗无反应。除1例患者外,其余患者均采用常规技术,超声心动图评分≤8分,平均孕周为28.5±6.4周。二尖瓣平均压差为19.8±6.4 mmHg,7例中有5例术后降至3.6±2.9 mmHg(P<0.01),瓣口面积从0.84±0.01增加至2.2±0.05(P<0.01)(P<0.05),二尖瓣反流轻微,无房间隔缺损病例。2例患者有中度至重度肺动脉高压,治疗后立即缓解。所有患者临床状态均有改善(P<0.001)。胎儿平均受辐射时间为7分钟,术中患者接受了2次经食管超声心动图检查。1例患者因主动脉穿孔行直视二尖瓣交界切开术,术后出现轻微血肿。2例患者在球囊扩张导致的低血压发作期间出现短暂胎儿心动过缓,无严重胎儿窘迫。除1例患者外,其余所有妊娠均足月;4例患者经阴道分娩,3例因产科指征行剖宫产。新生儿体重和阿氏评分均令人满意。我们认为,该手术的显著益处以及零孕产妇和胎儿死亡率使该技术成为治疗这种疾病的可接受方法。