Darie H, Le Guyadec T, Touze J E
CHR de Bouaké (Côte-d'Ivoire).
Bull Soc Pathol Exot. 1993;86(4):272-6.
A prospective study during 28 months at the Regional Hospital Center of Bouake (Ivory Coast) allows to gather 124 cases of Buruli ulcer. Today, this atypical cutaneous mycobacteriosis is in full expansion in West Africa. The pathogen agent, Mycobacterium ulcerans, causes, by its toxin, a subcutaneous necrosis often extended, followed by an ulceration which clinical characteristics are sufficient for the diagnostic. The endemic progression reason may not be caused by the modification of patients receptivity, but rather by the natural environment modification. In particular, the improving number of some soft water fish (Tilapia) which could have a germ tank.
在布瓦凯地区医院中心(科特迪瓦)进行的一项为期28个月的前瞻性研究收集到了124例布鲁里溃疡病例。如今,这种非典型皮肤分枝杆菌病正在西非迅速蔓延。病原体溃疡分枝杆菌通过其毒素导致常常广泛的皮下坏死,随后出现溃疡,其临床特征足以用于诊断。地方病进展的原因可能不是患者易感性的改变,而是自然环境的改变。特别是一些可能带有病菌池的淡水鱼(罗非鱼)数量在增加。