Sëmina O V, Semenets T N, Deĭgin V I, Korotkov A M, Poverennyĭ A M
Radiats Biol Radioecol. 1993 Nov-Dec;33(6):808-11.
The radiotherapeutic effect of thymogen (Glu-Trp) and thymohexin (Arg-Lys-Asp-Val-Tyr-Arg) synthetic peptide immunomodulators was investigated. Both thymogen and thymohexin were demonstrated to be able to reduce the damaging effect of ionizing radiation (1 Gy) on CFU-S by half. The treatment by these preparations after irradiation at dose of 4 Gy leads to more intensive restoration of CFU-S population as compared with control.
研究了胸腺生成素(Glu-Trp)和胸腺五肽(Arg-Lys-Asp-Val-Tyr-Arg)合成肽免疫调节剂的放射治疗效果。胸腺生成素和胸腺五肽均被证明能够将电离辐射(1 Gy)对脾集落形成单位(CFU-S)的损伤作用减半。与对照组相比,在4 Gy剂量照射后用这些制剂进行治疗可导致CFU-S群体更强烈地恢复。