辐射及其他淋巴因子对犬和大鼠淋巴组织影响的比较研究：细胞中的染色质降解、DNA与蛋白质合成
[Comparative study of the effect of radiation and other lymphatic agents on lymphoid tissue of dogs and rats: chromatin degradation, DNA and protein synthesis in cells].
作者信息
Ermolaeva N V, Aphonin A N, Ushenkova L N
出版信息
Radiats Biol Radioecol. 1993 Nov-Dec;33(6):867-73.
PMID:8293113
Abstract
It is established that lymphatic tissue of dogs shows far less degradation of chromatin after whob body irradiation (6 Gy) or exposure to lympholytic agents (hydrocortisone and colchicine), compared to rats. The fragmentation of chromatin in dog thymus occurs, like in rat, according to the internucleosome type, but affects a considerably less part of the thymocyte population.
摘要
已经确定，与大鼠相比，犬的淋巴组织在全身照射（6戈瑞）或暴露于淋巴细胞溶解剂（氢化可的松和秋水仙碱）后，染色质降解程度要低得多。犬胸腺中染色质的碎片化与大鼠一样，按照核小体间类型发生，但受影响的胸腺细胞群体比例要小得多。
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