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未免疫和已免疫供体血浆置换中免疫球蛋白G的动力学

Kinetics of immunoglobulin G in plasmapheresis of non-immunized and immunized donors.

作者信息

Serafimov-Dimitrov V, Ivanova L

出版信息

Haematologia (Budap). 1976;10(3-4):373-7.

PMID:829332
Abstract

The balance of immunoglobulins G has been studied during plasmapheresis in donors immunized and non-immunized with D antigen. For 42 days, the life-span of IgG, rhythmical withdrawal of plasma was carried out. During the procedure, 50% or 100% of the extracellular IgG was lost. A rhythmic loss of IgG amounting to double its production is the upper limit which can still sufficiently be compensated by the organism.

摘要

对D抗原免疫和未免疫的献血者进行血浆置换时,研究了免疫球蛋白G的平衡情况。在42天内,对IgG的寿命进行了研究,有节奏地抽取血浆。在此过程中,细胞外IgG损失了50%或100%。IgG的有节奏损失达到其产生量的两倍,这是机体仍能充分补偿的上限。

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