Marchini G, Simoni M R, Bartolini F, Lindén A
Department of Pediatrics, KS-S Göran, Karolinska Hospital, Stockholm, Sweden.
Early Hum Dev. 1993 Nov 1;35(1):31-5. doi: 10.1016/0378-3782(93)90136-i.
Plasma cholecystokinin concentrations were measured with radioimmunoassay in breast fed infants in Sweden (n = 101) and formula fed infants in Italy (n = 119). Blood samples were collected from the infants during the first five postnatal days, just before feeding in a cross-sectional way. We found no significant difference in the hormone concentration in relation to age, in breast fed or in formula fed infants. Breast fed infants had significantly higher plasma hormone concentrations than formula fed infants during the postnatal period 0-5 days: 2.8 pmol/l (1-10 pmol/l), median (range) versus 2.2 pmol/l (1-25 pmol/l), (P < 0.02). It cannot be excluded that the results were influenced by the circumstances that the samples were collected from two separate populations. However, the higher hormone levels in breast fed infants may also be the expression of the fact that natural feeding per se promotes cholecystokinin secretion in newborn infants.
采用放射免疫分析法测定了瑞典母乳喂养婴儿（n = 101）和意大利配方奶喂养婴儿（n = 119）的血浆胆囊收缩素浓度。在出生后的头五天内，以横断面的方式在喂奶前采集婴儿的血样。我们发现，无论是母乳喂养婴儿还是配方奶喂养婴儿，激素浓度与年龄均无显著差异。在出生后0至5天期间，母乳喂养婴儿的血浆激素浓度显著高于配方奶喂养婴儿：分别为2.8 pmol/l（1 - 10 pmol/l），中位数（范围）和2.2 pmol/l（1 - 25 pmol/l），（P < 0.02）。不能排除结果受到从两个不同人群采集样本这一情况的影响。然而，母乳喂养婴儿中较高的激素水平也可能表明自然喂养本身会促进新生儿胆囊收缩素的分泌。
