磁共振成像改变作为克雅氏病的早期发现

MRI alterations as an early finding in Creutzfeld-Jakob disease.

作者信息

Tartaro A, Fulgente T, Delli Pizzi C, Bonomo L, Bocola V, Onofrj M

机构信息

Institute of Neurological Sciences, University G. D'Annunzio of Chieti, Italy.

出版信息

Eur J Radiol. 1993 Nov;17(3):155-8. doi: 10.1016/0720-048x(93)90095-5.

DOI:10.1016/0720-048x(93)90095-5

PMID:8293740

Abstract

Two cases of Creutzfeldt-Jakob Disease (CJD) are reported. In both cases, pathologically confirmed, magnetic resonance imaging (MRI) showed bilateral altered signal areas in the basal ganglia, early in the course of the disease. The CT scan, although performed later than MRI, confirmed these findings. Only in one patient did electroencephalography (EEG) show typical triphasic sharp-waves, but this support to clinical diagnosis was obtained 1 month after the appearance of MRI alterations.

摘要

报告了2例克雅氏病（CJD）。在这两例经病理证实的病例中，磁共振成像（MRI）显示在疾病早期基底神经节出现双侧信号改变区域。计算机断层扫描（CT）虽然比MRI检查时间晚，但证实了这些发现。仅1例患者脑电图（EEG）显示典型的三相尖波，但在MRI改变出现1个月后才获得这一对临床诊断的支持。