[人乳腺纤维腺瘤细胞中D型病毒GS抗原的检测]
[Detection of the GS-antigen of D-type virus in the cells of human breast fibroadenoma].
作者信息
Il'in K V
出版信息
Biull Eksp Biol Med. 1976 Oct;82(10):1240-1.
Gs-antigen(s) of the D-type virus isolated from the continuous cells of human carcinoma was detected by the immunodiffusion with an indirect radioimmunoautographic assay in 5 of 7 human breast fibroadenoma. This virus contained gs-antigen common with the MPMV. These data demonstrated the genom of the D-type virus (or of a similar virus) to be integrated with the human fibroadenoma cells genom. Expression of the virus genom takes place at least to the level of the virus gs-antigen synthesis. The D-type virus from the continuous cell cultures of human carcinoma was associated with some human tumours, one of which was fibroadenoma.
采用免疫扩散间接放射免疫自显影法，在7例人乳腺纤维腺瘤中的5例中检测到从人癌连续细胞中分离出的D型病毒的Gs抗原。这种病毒含有与MPMV共有的gs抗原。这些数据表明D型病毒（或类似病毒）的基因组与人纤维腺瘤细胞基因组整合。病毒基因组至少在病毒gs抗原合成水平上表达。来自人癌连续细胞培养物的D型病毒与一些人类肿瘤有关，其中之一是纤维腺瘤。
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