Yamada S, Ohta K, Obata H, Matsushita S, Hirata I, Kudoh Y
Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health.
Kansenshogaku Zasshi. 1993 Dec;67(12):1183-9. doi: 10.11150/kansenshogakuzasshi1970.67.1183.
In 1992, the number of cases of shigellosis in Tokyo increased remarkably, and a total of 10 separate outbreaks were confirmed. Except for 1 series where the causative strains was Shigella flexneri 3a, the other 9 outbreaks were caused by Shigella sonnei. Of note, 7 outbreaks were familial with less than 5 patients. The remaining 3 outbreaks occurred in a restaurant, a school and the dormitory of an orphanage, in which the organism was detected in 6 to 14 patients. In 4 of the familial outbreaks occurring in distant areas during August, ark shell was presumed to be the vehicle by epidemiological investigations and laboratory examinations. Analysis of isolates such as the antibiotic resistance pattern, plasmid profile, or colicine type in Shigella sonnei was useful in clarifying the commonality of each case and identifying the vehicle or transmission.
1992年，东京志贺氏菌病病例数显著增加，共确认了10起独立的疫情暴发。除1起疫情的致病菌株为福氏志贺氏菌3a外，其他9起疫情由宋内志贺氏菌引起。值得注意的是，7起疫情为家庭聚集性，患者少于5人。其余3起疫情分别发生在一家餐馆、一所学校和一家孤儿院的宿舍，其中6至14名患者检测出该病菌。在8月发生在偏远地区的4起家庭聚集性疫情中，通过流行病学调查和实验室检查推测魁蚶为传播媒介。对宋内志贺氏菌的分离株进行抗生素耐药模式、质粒图谱或大肠杆菌素类型等分析，有助于明确每个病例的共性并确定传播媒介或传播途径。
