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澳大利亚中部志贺氏菌感染的分子流行病学

Molecular epidemiology of Shigella infection in Central Australia.

作者信息

Albert M J, Singh K V, Murray B E, Erlich J

机构信息

Alice Springs Hospital, Northern Territory, Australia.

出版信息

Epidemiol Infect. 1990 Aug;105(1):51-7. doi: 10.1017/s0950268800047634.

DOI:10.1017/s0950268800047634
PMID:2200701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2271788/
Abstract

Shigellosis is endemic in Central Australia and the infections are predominantly due to Shigella flexneri 6, Shigella flexneri 2a and Shigella sonnei. Plasmid profiles of isolates collected from 1985-9, suggested that infections caused by Shigella flexneri 6 were predominantly due to a single clone, whereas those caused by Shigella flexneri 2a and Shigella sonnei were due to several genetically diverse strains, although strains with identical plasmid profiles were found in widely separated geographical areas and in different years.

摘要

志贺氏菌病在澳大利亚中部地区流行,感染主要由福氏志贺氏菌6型、福氏志贺氏菌2a型和宋内志贺氏菌引起。1985年至199年收集的分离株的质粒图谱表明,福氏志贺氏菌6型引起的感染主要归因于单一克隆,而福氏志贺氏菌2a型和宋内志贺氏菌引起的感染则归因于几种基因不同的菌株,尽管具有相同质粒图谱的菌株在广泛分离的地理区域和不同年份被发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f39/2271788/c6df7b02f303/epidinfect00022-0055-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f39/2271788/f33fd16efb34/epidinfect00022-0052-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f39/2271788/c6df7b02f303/epidinfect00022-0055-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f39/2271788/f33fd16efb34/epidinfect00022-0052-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f39/2271788/c6df7b02f303/epidinfect00022-0055-a.jpg

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引用本文的文献

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3
Shigella sonnei strains isolated from U.S. summer students in Guadalajara, Mexico, from 1986 to 1992.

本文引用的文献

1
Rapid procedure for detection and isolation of large and small plasmids.用于检测和分离大小质粒的快速方法。
J Bacteriol. 1981 Mar;145(3):1365-73. doi: 10.1128/jb.145.3.1365-1373.1981.
2
Shigella sonnei plasmids: evidence that a large plasmid is necessary for virulence.宋内志贺氏菌质粒:证明一个大质粒对致病性是必需的证据。
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Drug resistance and plasmid profile of shigellae in Taiwan.台湾地区志贺氏菌的耐药性与质粒图谱
Epidemiol Infect. 1992 Feb;108(1):87-97. doi: 10.1017/s0950268800049530.
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Limitations of using the plasmid pattern as an epidemiological tool for clinical isolates of Shigella sonnei.将质粒图谱用作宋内志贺菌临床分离株流行病学工具的局限性。
J Infect Dis. 1987 Feb;155(2):314-6. doi: 10.1093/infdis/155.2.314.
5
Plasmid analysis of Shigella dysenteriae type 1 isolates obtained from widely scattered geographical locations.对从广泛分布的地理位置分离得到的1型痢疾志贺菌进行质粒分析。
J Clin Microbiol. 1988 Oct;26(10):2083-6. doi: 10.1128/jcm.26.10.2083-2086.1988.
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Electropherotyping of plasmid DNA of different serotypes of Shigella flexneri isolated in Bangladesh.对在孟加拉国分离出的不同血清型福氏志贺菌的质粒DNA进行电泳分型。
Epidemiol Infect. 1989 Jun;102(3):421-8. doi: 10.1017/s0950268800030132.
7
Simple agarose gel electrophoretic method for the identification and characterization of plasmid deoxyribonucleic acid.用于鉴定和表征质粒脱氧核糖核酸的简易琼脂糖凝胶电泳方法。
J Bacteriol. 1976 Sep;127(3):1529-37. doi: 10.1128/jb.127.3.1529-1537.1976.
8
A rapid alkaline extraction procedure for screening recombinant plasmid DNA.一种用于筛选重组质粒DNA的快速碱性提取方法。
Nucleic Acids Res. 1979 Nov 24;7(6):1513-23. doi: 10.1093/nar/7.6.1513.
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Isolation of covalently closed circular DNA of high molecular weight from bacteria.从细菌中分离高分子量共价闭合环状DNA。
Anal Biochem. 1976 Dec;76(2):431-41. doi: 10.1016/0003-2697(76)90338-9.