Lukomskiĭ G I, Ivanova N A, Kabanova G M, Semikov V I
Khirurgiia (Mosk). 1993 Oct(10):58-62.
Retrospective analysis of 94 patients who were operated on in the clinic in 1981-1987 for differentiated carcinoma of the thyroid was conducted with the use of the classification of the disease formulated by the American United Cancer Committee and the Committee TNM of the International Anticancer Union which takes into account the patients's age. According to the new system of stages, 34 patients under 45 years of age with any indices of T, N, and MO, and 14 patients over 45 years of age with indices Tl, NO, and MO were related to stage I. The postoperative follow-up period ranges from 4 to 9.5 years. During that time, metastases to the regional lymph nodes developed in 9 (9.5%) patients, remote metastases in one (1.1%) patient, and local recurrence of the tumor was diagnosed in 14 (14.5%) patients, with the tumor recurring in most or them 5 years after the operation. Six (6.4%) patients died from carcinoma. The work appraises the prognostic significance of dividing the patients according to stages from the standpoint of the tendency to recur and metastasize, and the carcinoma mortality rate. It is shown that patients who underwent operation for thyroid carcinoma must be kept under observation for a long time.
对1981年至1987年在该诊所接受手术治疗的94例甲状腺分化癌患者进行了回顾性分析,采用了美国联合癌症委员会和国际抗癌联盟TNM委员会制定的疾病分类方法,该方法考虑了患者的年龄。根据新的分期系统,34例45岁以下且T、N、M为任何指标的患者,以及14例45岁以上且指标为T1、N0、M0的患者属于I期。术后随访时间为4至9.5年。在此期间,9例(9.5%)患者出现区域淋巴结转移,1例(1.1%)患者出现远处转移,14例(14.5%)患者被诊断为肿瘤局部复发,其中大多数患者在术后5年复发。6例(6.4%)患者死于癌症。这项工作从复发和转移倾向以及癌症死亡率的角度评估了根据分期对患者进行划分的预后意义。结果表明,接受甲状腺癌手术的患者必须长期接受观察。