Gerster J C
Service de rhumatologie, médecine physique et réhabilitation, CHUV, Lausanne.
Schweiz Rundsch Med Prax. 1993 Nov 30;82(48):1381-3.
An insufficient compliance is regularly observed in 30% of outpatients. In chronic rheumatic diseases such as rheumatoid arthritis a poor compliance is often associated with alleviation of symptoms whereas symptomatic patients tend to take their medication more regularly. Drug abuse, mainly corticosteroids, can often not be avoided. The latter may 'particularly in women' lead to osteoporosis with subsequent fractures. In patients with fibrositis compliance is often a poor because of digestive problems associated with NSAIDs and the bad response to drugs and adjuvant therapies.
在30%的门诊患者中经常观察到依从性不足。在类风湿关节炎等慢性风湿性疾病中,依从性差往往与症状缓解有关,而有症状的患者往往更规律地服药。药物滥用,主要是皮质类固醇,往往无法避免。后者“尤其在女性中”可能导致骨质疏松症及随后的骨折。在纤维肌炎患者中,由于与非甾体抗炎药相关的消化问题以及对药物和辅助治疗的不良反应,依从性往往很差。