Neĭmark A I, Astakhov Iu I, Davydov A V, Mazyrko A V, Iakovets Ia V
Ter Arkh. 1993;65(10):83-6.
The paper presents the results of plasmapheresis inclusion into a combined therapy of pyelonephritis. Out of 79 patients treated, 42 had urosepsis, 25 developed pyelonephritis in pregnancy, 12 had complicating chronic renal failure. Uroseptic patients were examined for hemostasis, the rest for immune status. There were symptoms of DIC syndrome in the former and immunity suppression in the latter. After the combined therapy with plasmapheresis, latent hypercoagulation and intoxication disappeared, uroseptic manifestations reduced. The above treatment of pregnancy pyelonephritis stopped inflammation, promoted activation of the immune system. In patients with chronic renal failure adjuvant plasmapheresis enhanced cellular and humoral immunity, neutrophil function, the number of middle-size molecules in the blood diminished. The latter improved renal function in decreasing uremia.
本文介绍了血浆置换纳入肾盂肾炎联合治疗的结果。在接受治疗的79例患者中，42例患有尿脓毒症，25例在妊娠期间发生肾盂肾炎，12例并发慢性肾衰竭。对尿脓毒症患者进行止血检查，其余患者进行免疫状态检查。前者有弥散性血管内凝血综合征的症状，后者有免疫抑制。血浆置换联合治疗后，潜在的高凝状态和中毒消失，尿脓毒症表现减轻。上述妊娠肾盂肾炎的治疗停止了炎症，促进了免疫系统的激活。在慢性肾衰竭患者中，辅助性血浆置换增强了细胞免疫和体液免疫、中性粒细胞功能，血液中中等大小分子的数量减少。后者通过降低尿毒症改善了肾功能。
