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[慢性肾盂肾炎和慢性肾衰竭患者免疫紊乱的纠正]

[The correction of the immune disorders in patients with chronic pyelonephritis and chronic kidney failure].

作者信息

Neĭmark A I, Iakovets Ia V

出版信息

Urol Nefrol (Mosk). 1994 Sep-Oct(5):22-4.

PMID:7532880
Abstract

The trial entered 41 patients with chronic renal failure. Group I (15 patients) received conventional therapy involving infusion detoxication, antibiotics, immunostimulators, anabolic agents. 26 patients of group II in addition to standard therapeutic measures underwent plasmapheresis. The effect was assessed by immunological and renal function parameters. Group I patients have benefited from conventional treatment, but signs of immunodeficiency remained: B-lymphocyte, IgG and IgA levels were lowered and elevated, respectively. Patients of group II improved clinically, got rid of uremia and immunodeficiency.

摘要

该试验纳入了41例慢性肾衰竭患者。第一组(15例患者)接受了包括输液解毒、抗生素、免疫刺激剂、同化激素在内的传统治疗。第二组的26例患者除了接受标准治疗措施外,还进行了血浆置换。通过免疫学和肾功能参数评估疗效。第一组患者从传统治疗中受益,但免疫缺陷迹象仍然存在:B淋巴细胞、IgG和IgA水平分别降低和升高。第二组患者临床症状改善,摆脱了尿毒症和免疫缺陷。

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