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[1943 - 1985年丹麦的新生儿癌症]

[Neonatal cancer in Denmark 1943-1985].

作者信息

Børch K, Jacobsen T, Olsen J H, Hirsch F R, Hertz H

机构信息

Børneafdeling GGK, Rigshospitalet, København.

出版信息

Ugeskr Laeger. 1994 Jan 10;156(2):176-9.

PMID:8296406
Abstract

In order to describe the incidence, distribution and prognosis of neonatal cancer, 76 cases (44 boys, 32 girls) of cancer in the first 28 days of life were identified in the Danish Cancer Registry within the period 1943-85. All cases were re-evaluated and the International Classification of Disease for Oncology (ICD-O) code was applied. The incidence is calculated to 2.38 (1.88-2.98) cases per 100,000 births. The most common tumour was neuroblastoma (26%) followed by leukaemias (16%), soft tissue sarcomas (14%) and brain tumours (11%). The five year survival rate was 25% (15.1-39.0) with the highest survival rate among soft tissue sarcomas (55%) and neuroblastomas (25%) and the lowest among leukaemias and brain tumours (0). Eighteen per cent of the cases were incidental findings. Two cases of secondary malignancy were identified.

摘要

为描述新生儿癌症的发病率、分布及预后情况,在丹麦癌症登记处中确定了1943年至1985年期间出生后前28天内患癌的76例患儿(44例男孩,32例女孩)。对所有病例重新进行了评估,并应用了国际肿瘤疾病分类(ICD - O)编码。计算得出发病率为每10万例出生中有2.38例(1.88 - 2.98例)。最常见的肿瘤是神经母细胞瘤(26%),其次是白血病(16%)、软组织肉瘤(14%)和脑肿瘤(11%)。五年生存率为25%(15.1 - 39.0),其中软组织肉瘤的生存率最高(55%),神经母细胞瘤次之(25%),白血病和脑肿瘤的生存率最低(0)。18%的病例为偶然发现。确定了2例继发性恶性肿瘤病例。

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