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美国预暴露对条件性味觉厌恶的影响:厌恶反应在条件化后未恢复。

The effect of US preexposure on conditioned taste aversion: lack of postconditioning recovery of the aversion.

作者信息

Cole K C, Bakner L, Vernon A, Riccio D C

机构信息

Department of Psychology, Kent State University, Ohio 44242.

出版信息

Behav Neural Biol. 1993 Nov;60(3):271-3. doi: 10.1016/0163-1047(93)90523-k.

DOI:10.1016/0163-1047(93)90523-k
PMID:8297323
Abstract

Although the CS preexposure effect in CTA was once viewed exclusively as an acquisition failure, recent studies have suggested that the latent inhibition phenomenon is the result of retrieval impairment. This interpretive challenge is based on the unexpected finding that recovery of the aversion occurs over a long retention interval following conditioning (Kraemer, Lariviere, & Spear, Animal Learning and Behavior, 16, 185-190, 1988; Bakner, Strohen, Nordeen, & Riccio, Physiology & Behavior, 50, 1269-1272, 1991). This study examined whether a similar recovery occurs after US preexposure. Following preexposure to the US (LiCl), rats received a sucrose-illness pairing and were subsequently tested after either short or long training-to-test intervals. In contrast to the findings with the CS preexposure effect, US-preexposed subjects did not show a spontaneous increase in CTA following the long retention interval.

摘要

尽管条件性味觉厌恶(CTA)中的条件刺激(CS)预暴露效应曾一度被单纯视为习得失败,但最近的研究表明,潜伏抑制现象是提取障碍的结果。这一解释上的挑战基于一个意外发现,即厌恶反应在条件作用后的长时间保持间隔内会恢复(克雷默、拉里维埃尔和斯皮尔,《动物学习与行为》,第16卷,第185 - 190页,1988年;巴克纳、斯特罗恩、诺丁和里乔,《生理学与行为》,第50卷,第1269 - 1272页,1991年)。本研究考察了在非条件刺激(US)预暴露后是否会出现类似的恢复情况。在对大鼠进行氯化锂(LiCl)非条件刺激预暴露后,使其接受蔗糖 - 疾病配对,随后在短或长的训练至测试间隔后进行测试。与条件刺激预暴露效应的研究结果相反,非条件刺激预暴露的实验对象在长时间保持间隔后并未表现出条件性味觉厌恶的自发增加。

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