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负鼠副嗅球中OMP的差异表达

Differential OMP expression in opossum accessory olfactory bulb.

作者信息

Shnayder L, Schwanzel-Fukuda M, Halpern M

机构信息

Program in Neural and Behavioral Sciences, Health Science Center at Brooklyn, State University, NY 11203.

出版信息

Neuroreport. 1993 Dec 13;5(3):193-6. doi: 10.1097/00001756-199312000-00001.

DOI:10.1097/00001756-199312000-00001
PMID:8298073
Abstract

Using immunohistochemical techniques, olfactory marker protein (OMP) was localized to the main (MOB) and accessory (AOB) olfactory bulbs of 30- and 45-day-old, and adult Brazilian opossums, Monodelphis domestica. Entire olfactory nerve and glomerular layers of the adult opossum MOB were darkly stained. In the adult AOB the rostral half of these two layers was stained more intensely than the caudal half, and both parts were less darkly stained than the MOB. This differential AOB staining was not present at 30 days of age, but was evident by postnatal day 45, although not as dramatic as in adults. This is the first report of differential OMP expression and may provide an approach to identifying the function of OMP.

摘要

利用免疫组织化学技术,在30日龄、45日龄的成年巴西负鼠(Monodelphis domestica)的主嗅球(MOB)和副嗅球(AOB)中定位了嗅觉标记蛋白(OMP)。成年负鼠主嗅球的整个嗅神经层和肾小球层均被深染。在成年副嗅球中,这两层的前半部分比后半部分染色更强烈,且两部分的染色深度均低于主嗅球。这种副嗅球染色差异在30日龄时不存在,但在出生后第45天明显,尽管不如成年时显著。这是关于OMP差异表达的首次报道,可能为确定OMP的功能提供一种方法。

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