在根治性前列腺切除术前行经直肠超声检查以评估前列腺癌的局部范围。
Transrectal ultrasonography to assess local extent of prostatic cancer before radical prostatectomy.
作者信息
Rørvik J, Halvorsen O J, Servoll E, Haukaas S
机构信息
Department of Diagnostic Radiology, Gade Institute, University of Bergen, Norway.
出版信息
Br J Urol. 1994 Jan;73(1):65-9. doi: 10.1111/j.1464-410x.1994.tb07458.x.
OBJECTIVE
To evaluate transrectal ultrasonography (TRUS) with a 7 mHz rotating probe as a staging procedure in 33 patients with localized prostatic carcinoma.
PATIENTS AND METHODS
The ultrasound scans were compared to histopathological whole-mount step sections of the surgical specimens. Twenty-five of the patients had tumours with pathological stage T3 (pT3) and eight had tumours with stage pT2 giving a prevalence of extracapsular growth of 0.76.
RESULTS
The overall sensitivity, specificity, positive and negative predictive values for detection of extracapsular tumour growth by TRUS of prostatic cancer were found to be 0.68, 0.63, 0.85 and 0.38, respectively. Six tumours showed solely microscopic foci of extracapsular tumour growth.
CONCLUSION
This technique gives a high percentage of both understaging (32%) and overstaging (37%) and therefore TRUS is an unreliable tool in the staging protocol prior to radical prostatectomy.
目的
评估采用7兆赫兹旋转探头的经直肠超声检查（TRUS）作为33例局限性前列腺癌患者分期检查方法的效果。
患者与方法
将超声扫描结果与手术标本的组织病理学全层连续切片进行比较。25例患者的肿瘤病理分期为T3（pT3）期，8例患者的肿瘤为pT2期，包膜外生长的发生率为0.76。
结果
经直肠超声检查前列腺癌包膜外肿瘤生长的总体敏感度、特异度、阳性预测值和阴性预测值分别为0.68、0.63、0.85和0.38。6例肿瘤仅显示包膜外肿瘤生长的微小病灶。
结论
该技术存在较高比例的分期过低（32%）和分期过高（37%）情况，因此在根治性前列腺切除术之前的分期方案中，经直肠超声检查是一种不可靠的工具。
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