el-Din M S, el-Refai M I, el-Kafrawi A O, el-Badawi S
Oral Medicine and Periodontology, Faculty of Oral and Dental Medicine, Cairo University.
Egypt Dent J. 1993 Jan;39(1):387-94.
Patients undergoing radiotherapy for malignant tumors of the head and neck invariably develop extensive oral and dental diseases particularly when the major salivary glands are within the radiation fields. Unless the patient receives a strict oral hygiene home care and the teeth are protected by topical application of fluoride gel, caries or gingival disease onset inevitably follows radiation induced xerostomia is. The importance of saliva as a controlling factor in the development of oral diseases is underscored by the dramatic increase in dental decay and gingival diseases that inevitably follows the surgical extirpation of the major salivary glands in animals and the onset of xerostomia in man.
接受头颈部恶性肿瘤放射治疗的患者不可避免地会患上广泛的口腔和牙齿疾病，尤其是当主要唾液腺位于放射野内时。除非患者在家中接受严格的口腔卫生护理，并且通过局部应用氟凝胶来保护牙齿，否则龋齿或牙龈疾病的发生将不可避免地伴随辐射诱导的口干症而来。唾液作为口腔疾病发展的控制因素的重要性，通过动物主要唾液腺手术切除后不可避免地出现的龋齿和牙龈疾病的急剧增加以及人类口干症的发作得到了强调。
