Sauerwein R W, Bisseling J, Horrevorts A M
Dept. of Medical Microbiology, University Hospital Nijmegen, The Netherlands.
Infection. 1993 Sep-Oct;21(5):331-3. doi: 10.1007/BF01712458.
In contrast to the situation in cattle, goat and sheep, Campylobacter fetus subspecies fetus only rarely causes disease in humans. While a major inducer of septic abortion in animals, only a minority of clinical infections in humans are found during pregnancy. Eleven cases have so far been described in pregnant women. Clinical symptomatology is usually mild during gestation but often leads to premature labor. Here we present a multigravida with positive cultures for C. fetus who went into septic shock. She completely recovered after delivery of a C. fetus-infected fetus at 18 weeks' gestation and treatment with a combination of cephazolin and gentamicin. C. fetus infections should be suspected in patients with intensive contact with (infected) cattle or after intake of unpasteurized dairy products.
与牛、山羊和绵羊的情况不同，胎儿弯曲杆菌胎儿亚种在人类中很少引起疾病。虽然它是动物败血症性流产的主要诱因，但人类临床感染中只有少数发生在孕期。迄今为止，已报道了11例孕妇感染病例。孕期临床症状通常较轻，但常导致早产。在此，我们报告一例多次妊娠孕妇，其胎儿弯曲杆菌培养呈阳性，发生了感染性休克。在妊娠18周时分娩出感染胎儿弯曲杆菌的胎儿，并接受头孢唑林和庆大霉素联合治疗后，她完全康复。与（感染的）牛有密切接触的患者或摄入未巴氏杀菌乳制品后，应怀疑感染胎儿弯曲杆菌。
