Scheuermann D W
Laboratory of Cell Biology and Histology, University of Antwerp, Belgium.
J Anat. 1993 Oct;183 ( Pt 2)(Pt 2):327-42.
Chromaffin cells were observed singly or in clusters in the heart and sympathetic cord of 2 genera of dipnoan fish, Protopterus and Lepidosiren. They were invariably found in close association with the autonomic sympathetic nervous system and at sites where chromaffin cells or their precursors are situated in mammals during ontogenetic development. X-ray microanalysis demonstrated that they contained a primary catecholamine which was identified microspectrofluorometrically as dopamine. The chromaffin cells were innervated by efferent axons with typical preganglionic sympathetic terminals which were acetylcholinesterase-positive. Although the general morphology and cytochemistry agree with those of developing intra-adrenal chromaffin cells in mammals, the morphological characteristics implicate them as active secretory gland cells. The dopamine transmitter phenotype seems to be determined by the maintenance throughout life of the separate and distant location of steroidogenic interrenal tissue from suprarenal elements.
在非洲肺鱼属的原鳍鱼和美洲肺鱼这两个属的肺鱼的心脏和交感神经索中，嗜铬细胞单个或成群分布。它们总是与自主交感神经系统紧密相连，且位于哺乳动物个体发育过程中嗜铬细胞或其前体所在的部位。X射线微量分析表明，它们含有一种主要的儿茶酚胺，经显微分光荧光测定法鉴定为多巴胺。嗜铬细胞由传出轴突支配，这些轴突具有典型的节前交感神经末梢，且乙酰胆碱酯酶呈阳性。尽管其总体形态和细胞化学与哺乳动物发育中的肾上腺内嗜铬细胞相符，但形态特征表明它们是活跃的分泌腺细胞。多巴胺递质表型似乎是由终生维持类固醇生成的肾间组织与肾上腺成分的分离和远距离位置所决定的。
