大肠杆菌的甘露醇阻遏物（MtlR）
The mannitol repressor (MtlR) of Escherichia coli.
作者信息
Figge R M, Ramseier T M, Saier M H
机构信息
Department of Biology, University of California at San Diego, La Jolla 92093-0116.
出版信息
J Bacteriol. 1994 Feb;176(3):840-7. doi: 10.1128/jb.176.3.840-847.1994.
Abstract
The mannitol operon of Escherichia coli, encoding the mannitol-specific enzyme II of the phosphotransferase system (Mt1A) and mannitol phosphate dehydrogenase (Mt1D), is here shown to contain a single additional downstream open reading frame which encodes the mannitol repressor (Mt1R). Mt1R contains 195 amino acids and has a calculated molecular weight of 21,990 and a calculated pI of 4.5. It is homologous to the product of an open reading frame (URF2D) upstream of the E. coli gapB gene but represents a novel type of transcriptional regulatory protein.
摘要
大肠杆菌的甘露醇操纵子编码磷酸转移酶系统的甘露醇特异性酶II（Mt1A）和甘露醇磷酸脱氢酶（Mt1D），本文显示该操纵子还包含一个额外的下游开放阅读框，其编码甘露醇阻遏物（Mt1R）。Mt1R含有195个氨基酸，计算分子量为21,990，计算的等电点为4.5。它与大肠杆菌gapB基因上游的一个开放阅读框（URF2D）的产物同源，但代表一种新型的转录调节蛋白。
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