Lakie M, Walsh E G, Arblaster L A, Villagra F, Roberts R C
Applied Physiology Research Unit, University of Birmingham, UK.
J Neurol Neurosurg Psychiatry. 1994 Jan;57(1):35-42. doi: 10.1136/jnnp.57.1.35.
The changes in postural tremor of the hand produced by moderate cooling of the muscles of one forearm have been investigated in 16 normal subjects and in 16 patients with essential tremor. In both groups, cooling produced a profound long lasting decrease in tremor level of the ipsilateral hand. In normal subjects, although cooling reduced the tremor size, the EMG of the active muscle clearly increased. Warming the limb in normal subjects produced an increase in tremor level and decrease in EMG. Cooling or warming the limb did not, however, significantly change the peak frequency which was quite stable for each subject. The results of cooling were compared with a brief period of ischaemia, which also reduces tremor size. Local cooling may be a useful manoeuvre for patients with essential tremor, and for others who wish to reduce their tremor temporarily in order to improve dexterity.
对16名正常受试者和16名特发性震颤患者进行了研究,观察了一侧前臂肌肉适度冷却对手部姿势性震颤的影响。在两组中,冷却均使同侧手部的震颤水平显著且持久降低。在正常受试者中,尽管冷却减小了震颤幅度,但主动肌的肌电图明显增加。正常受试者肢体升温会使震颤水平升高,肌电图降低。然而,冷却或加热肢体并未显著改变峰值频率,每个受试者的峰值频率相当稳定。将冷却的结果与短暂缺血的结果进行了比较,短暂缺血也会减小震颤幅度。局部冷却对于特发性震颤患者以及其他希望暂时减轻震颤以提高灵活性的人可能是一种有用的方法。