阿昔洛韦：它是一种治疗口腔面部感染的有效病毒抑制剂吗？

Acyclovir: is it an effective virostatic agent for orofacial infections?

作者信息

Lavelle C L

机构信息

University of Manitoba, Department of Oral Biology, Winnipeg, Canada.

出版信息

J Oral Pathol Med. 1993 Oct;22(9):391-401. doi: 10.1111/j.1600-0714.1993.tb00129.x.

DOI:10.1111/j.1600-0714.1993.tb00129.x

PMID:8301603

Abstract

Oral and intravenous acyclovir formulations provide effective virostasis against many herpes viruses infections, especially severe herpes simplex or varicella-zoster infections in ambulatory and immunocompromised patients. The therapeutic virostatic efficacy of topical acyclovir formulations requires further development, however, especially for orolabial herpetic infections.

摘要

口服和静脉注射阿昔洛韦制剂对多种疱疹病毒感染具有有效的病毒抑制作用，尤其是对门诊患者和免疫功能低下患者的严重单纯疱疹或水痘-带状疱疹感染。然而，局部用阿昔洛韦制剂的治疗性病毒抑制效果仍需进一步研发，特别是对于唇疱疹感染。