Canzonieri V, Volpe R, Gloghini A, Carbone A, Merlo A
Division of Pathology, Centro Regionale di Riferimento Oncologico di Aviano, Italy.
Pathol Res Pract. 1993 Sep;189(8):951-6; discussion 957-9. doi: 10.1016/S0344-0338(11)81110-6.
A 54-year-old woman, without the stigmas of tuberous sclerosis, underwent radical nephrectomy for simultaneous occurrence of an Angiomyolipoma (AML) and a carcinomatous and fibroleiomyomatous mixed tumor in the same kidney, diagnosed by computerized tomography, selective renal arteriography and anatomopathological examination. The peculiar findings of the mixed neoplasia, characterized by a mixture of carcinomatous and fibroleiomuscular components are stressed. The latter component is considered to be a proliferative element interacting with the carcinomatous one. After review of the pertinent literature, this is the first example of an association of AML and renal cell carcinoma (RCC) in which the RCC is constituted by a mixture of carcinomatous and fibroleiomyomatous cells.
一名54岁女性,无结节性硬化症的特征,因同一肾脏同时出现血管平滑肌脂肪瘤(AML)和癌性及纤维平滑肌瘤性混合肿瘤而接受根治性肾切除术,该诊断通过计算机断层扫描、选择性肾动脉造影及解剖病理学检查得以证实。文中强调了混合性肿瘤的独特发现,其特征为癌性成分与纤维平滑肌成分的混合。后一种成分被认为是与癌性成分相互作用的增殖性成分。查阅相关文献后发现,这是AML与肾细胞癌(RCC)关联的首例病例,其中RCC由癌性和纤维平滑肌瘤性细胞混合构成。