类二十烷酸与排卵

Eicosanoids and ovulation.

作者信息

Priddy A R, Killick S R

机构信息

Department of Obstetrics and Gynaecology, University Hospital of South Manchester, UK.

出版信息

Prostaglandins Leukot Essent Fatty Acids. 1993 Nov;49(5):827-31. doi: 10.1016/0952-3278(93)90204-a.

DOI:10.1016/0952-3278(93)90204-a

PMID:8302915

Abstract

PGs and probably other eicosanoids play a fundamental role in the process of ovulation, more specifically in the mechanism of follicle wall rupture. Although the nature of this role has yet to be established a number of plausible theories exist. It seems likely that altered PG metabolism is responsible for some cases of human female subfertility. The potential for fertility control by PG inhibition is an exciting possibility for the future.

摘要

前列腺素以及可能的其他类花生酸在排卵过程中发挥着重要作用，更具体地说是在卵泡壁破裂机制中。尽管这一作用的本质尚未确定，但存在一些合理的理论。在某些人类女性生育力低下的病例中，前列腺素代谢改变似乎是原因所在。通过抑制前列腺素进行生育控制的可能性为未来带来了令人兴奋的前景。